Methicillin

Methicillin
INN: Meticillin
Clinical data
Routes of; administration	IV
ATC code	J01CF03 (WHO) QJ51CF03 (WHO);
Pharmacokinetic data
Bioavailability	Not orally absorbed
Metabolism	hepatic, 20–40%
Elimination half-life	25–60 minutes
Excretion	renal
Identifiers
	IUPAC name (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
CAS Number	61-32-5 ;
PubChem CID	6087;
DrugBank	DB01603 ;
ChemSpider	5862 ;
UNII	Q91FH1328A;
ChEMBL	ChEMBL575 ;
CompTox Dashboard (EPA)	DTXSID6023284 ;
ECHA InfoCard	100.000.460
Chemical and physical data
Formula	C17H20N2O6S
Molar mass	380.42 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC(=O)[C@@H]2N3C(=O)[C@@H](NC(=O)c1c(OC)cccc1OC)[C@H]3SC2(C)C;
	(what is this?) (verify)

Methicillin (USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.

Methicillin was discovered in 1960.^[1]

Clinical data


Routes of administration	IV
ATC code	J01CF03 (WHO) QJ51CF03 (WHO)
Pharmacokinetic data
Bioavailability	Not orally absorbed
Metabolism	hepatic, 20–40%
Elimination half-life	25–60 minutes
Excretion	renal
Identifiers
IUPAC name (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number	61-32-5^Y
PubChem CID	6087
DrugBank	DB01603^Y
ChemSpider	5862^N
UNII	Q91FH1328A
ChEMBL	ChEMBL575^N
CompTox Dashboard (EPA)	DTXSID6023284
ECHA InfoCard	100.000.460
Chemical and physical data
Formula	C₁₇H₂₀N₂O₆S
Molar mass	380.42 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES OC(=O)[C@@H]2N3C(=O)[C@@H](NC(=O)c1c(OC)cccc1OC)[C@H]3SC2(C)C
^NY (what is this?) (verify)