Chromobacterium violaceum

Chromobacterium violaceum
Blood agar plate culture of C. violaceum. Image from the CDC.
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Pseudomonadota
Class: Betaproteobacteria
Order: Neisseriales
Family: Neisseriaceae
Genus: Chromobacterium
Species:
C. violaceum
Binomial name
Chromobacterium violaceum
(Bergonzini 1880)

Chromobacterium violaceum is a Gram-negative, facultative anaerobic, non-sporing coccobacillus. It is motile with the help of a single flagellum which is located at the pole of the coccobacillus. Usually, there are one or two more lateral flagella as well.[1] It is part of the normal flora of water and soil of tropical and sub-tropical regions of the world. It produces a natural antibiotic called violacein, which may be useful for the treatment of colon and other cancers.[2] It grows readily on nutrient agar, producing distinctive smooth low convex colonies with a characteristic striking dark violet metallic sheen (due to violacein production).[3] Some strains of the bacteria which do not produce this pigment have also been reported.[4] It has the ability to break down tarballs.[5]

  1. ^ Ray, P; Sharma, J; Marak, SK; Singhi, S; Taneja, N; Garg, RK (2004). "Chromobacterium violaceum septicaemia from North India". Indian J Med Res. 120 (6): 523–6. PMID 15654137.
  2. ^ Kodach LL, Bos CL, Durán N, Peppelenbosch MP, Ferreira CV, Hardwick JC (2006). "Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells". Carcinogenesis. 27 (3): 508–16. doi:10.1093/carcin/bgi307. PMID 16344270.
  3. ^ Brazilian National Genome Project Consortium (2003). "The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability". Proc Natl Acad Sci USA. 100 (20): 11660–5. Bibcode:2003PNAS..10011660.. doi:10.1073/pnas.1832124100. PMC 208814. PMID 14500782.
  4. ^ Lee, J; Kim, JS; Nahm, CH; Choi, JW; Kim, J; Pai, SH; Moon, KH; Lee, K; Chong, Y (1999). "Two Cases of Chromobacterium violaceum Infection after Injury in a Subtropical Region". J Clin Microbiol. 37 (6): 2068–2070. doi:10.1128/JCM.37.6.2068-2070.1999. PMC 85035. PMID 10325383.
  5. ^ Itah AY, Essien JP (2005). "Growth Profile and Hydrocarbonoclastic Potential of Microorganisms Isolated from Tarballs in the Bight of Bonny, Nigeria". World Journal of Microbiology and Biotechnology. 21 (6–7): 1317–22. doi:10.1007/s11274-004-6694-z. S2CID 84888286.

From Wikipedia, the free encyclopedia · View on Wikipedia

Developed by Nelliwinne