Back غاري روفكون Arabic جارى روفكون ARZ Гэры Раўкан Byelorussian Gary Ruvkun German Gary Ruvkun Spanish Gary Ruvkun Portuguese Равкан, Гэри Russian 加里·鲁夫昆 Chinese
Gary Bruce Ruvkun (born March 1952, Berkeley, California)[1] is an American molecular biologist at Massachusetts General Hospital and professor of genetics at Harvard Medical School in Boston.[2] Ruvkun discovered the mechanism by which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing to those targets, and discovered the second miRNA, let-7, and that it is conserved across animal phylogeny, including in humans. These miRNA discoveries revealed a new world of RNA regulation at an unprecedented small size scale, and the mechanism of that regulation. Ruvkun also discovered many features of insulin-like signaling in the regulation of aging and metabolism. He was elected a Member of the American Philosophical Society in 2019.
- ^ Who's Who in America 66th edition. Vol 2: M–Z. Marquis Who's Who, Berkeley Heights 2011, p. 3862
- ^ Nair, P. (2011). "Profile of Gary Ruvkun". Proceedings of the National Academy of Sciences. 108 (37): 15043–5. Bibcode:2011PNAS..10815043N. doi:10.1073/pnas.1111960108. PMC 3174634. PMID 21844349.