MRSA is methicillin-resistant Staphylococcus aureus, a bacterium.
MRSA may also refer to:
- MrsA (gene), for the enzyme 2-Ketoarginine methyltransferase
- Metrolina Regional Scholars' Academy, Charlotte, North Carolina, US
- San Alberto Airport (ICAO airport code), Costa Rica
- Mat Zo (born 1990), pseudonym MRSA, British producer and DJ