| Maria Komnene Doukaina | |
|---|---|
| Countess Palatine of Cephalonia and Zakynthos | |
| Predecessor | Marguerite de Villehardouin |
| Successor | Anna Palaiologina |
| Spouse | John I Orsini |
| Issue | Nicholas Orsini John II Orsini Guy Orsini Margaret Orsini |
| House | Komnenodoukas |
| Father | Nikephoros I Komnenos Doukas |
| Mother | Maria Laskaris Vatatzaina |
| Religion | Orthodox Christian |
Maria Komnene Doukaina (Greek: Μαρία Κομνηνή Δούκαινα) was an Epiriot princess, daughter of Nicephorus I, and countess palatine of Cephalonia and Zakynthos as wife of John I Orsini.