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Mutagenesis

This article is about mutagenesis as a general process. For mutagenesis as a laboratory technique, see Mutagenesis (molecular biology technique).

Mutagenesis (/mjuːtəˈdʒɛnɪsɪs/) is a process by which the genetic information of an organism is changed by the production of a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using laboratory procedures. A mutagen is a mutation-causing agent, be it chemical or physical, which results in an increased rate of mutations in an organism's genetic code. In nature mutagenesis can lead to cancer and various heritable diseases, and it is also a driving force of evolution. Mutagenesis as a science was developed based on work done by Hermann Muller, Charlotte Auerbach and J. M. Robson in the first half of the 20th century.[1]

  1. ^ Beale, G. (1993). "The Discovery of Mustard Gas Mutagenesis by Auerbach and Robson in 1941". Genetics. 134 (2): 393–399. doi:10.1093/genetics/134.2.393. PMC 1205483. PMID 8325476.
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