Back حبيبات نسل Arabic Cos de Nissl Catalan Nisslova substance Czech Nissl-Schollen German Cuerpos de Nissl Spanish Nissli substants Estonian جسم نیسل Persian Corps de Nissl French Corpo de Nissl Galician גופי ניסל HE
In cellular neuroscience, Nissl bodies (also called Nissl granules, Nissl substance or tigroid substance) are discrete granular structures in neurons that consist of rough endoplasmic reticulum, a collection of parallel, membrane-bound cisternae studded with ribosomes on the cytosolic surface of the membranes.[1] Nissl bodies were named after Franz Nissl, a German neuropathologist who invented the staining method bearing his name (Nissl staining).[2][3] The term "Nissl bodies" generally refers to discrete clumps of rough endoplasmic reticulum and free ribosomes in nerve cells. Masses of rough endoplasmic reticulum also occur in some non-neuronal cells, where they are referred to as ergastoplasm, basophilic bodies,[1] or chromophilic substance.[4] While these organelles differ in some ways from Nissl bodies in neurons,[5] large amounts of rough endoplasmic reticulum are generally linked to the copious production of proteins.[1]
- ^ a b c Junqueira LC, Carniero J, Kelley RO (1995). Basic Histology. Appleton & Lange. ISBN 0-8385-0567-8.
- ^ Richard H. Thompson (29 March 2000). The Brain: A Neuroscience Primer. Macmillan. pp. 35–. ISBN 978-0-7167-3226-6. Retrieved 4 January 2013.
- ^ Da Mota Gomes M (2019). "Franz Nissl (1860-1919), noted neuropsychiatrist and neuropathologist, staining the neuron, but not limiting it". Dementia & Neuropsychologia. 13 (3): 352–355. doi:10.1590/1980-57642018dn13-030014. PMC 6753910.
- ^ Fawcett, Don W. (1966). The Cell: Its Organelles and Inclusions. W.B. Saunders Company. ISBN 0-7216-3585-7.
- ^ Peters A, Palay SL, Webster Hd (1991). The Fine Structure of the Nervous System. Oxford University Press. ISBN 0-19-506571-9.