Back Nukleofilní acylová substituce Czech Nukleofil acylsubstitution Danish Additions-Eliminierungs-Mechanismus German Sustitución nucleófila acílica Spanish جانشینی هسته دوستی آسیل Persian Nukleofiilinen asyylisubstituutio Finnish Substitution nucléophile d'acyle French התמרה נוקלאופילית אצילית HE Acil nukleofil szubsztitúció Hungarian Substitusi asil nukleofilik ID
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Nucleophilic acyl substitution (SNAcyl) describes a class of substitution reactions involving nucleophiles and acyl compounds. In this type of reaction, a nucleophile – such as an alcohol, amine, or enolate – displaces the leaving group of an acyl derivative – such as an acid halide, anhydride, or ester. The resulting product is a carbonyl-containing compound in which the nucleophile has taken the place of the leaving group present in the original acyl derivative. Because acyl derivatives react with a wide variety of nucleophiles, and because the product can depend on the particular type of acyl derivative and nucleophile involved, nucleophilic acyl substitution reactions can be used to synthesize a variety of different products.