Mephentermine

Mephentermine
Clinical data
Other names	methyl(2-methyl-1-phenylpropan-2-yl)amine
Routes of; administration	IM/IV
ATC code	C01CA11 (WHO) ;
Legal status
Legal status	US: Schedule I (positional isomer of Etilamfetamine);
Pharmacokinetic data
Metabolism	Rapidly demethylated in the body followed by hydroxylation.
Excretion	Via urine (as unchanged and metabolites); more rapid in acidic urine.
Identifiers
	IUPAC name N,2-dimethyl-1-phenylpropan-2-amine;
CAS Number	100-92-5 ;
PubChem CID	3677;
IUPHAR/BPS	7222;
DrugBank	DB01365 ;
ChemSpider	3549 ;
UNII	TEZ91L71V4;
KEGG	D08180 ;
ChEMBL	ChEMBL1201234 ;
CompTox Dashboard (EPA)	DTXSID4023256 ;
ECHA InfoCard	100.002.638
Chemical and physical data
Formula	C11H17N
Molar mass	163.264 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES N(C(Cc1ccccc1)(C)C)C;
	InChI InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3 ; Key:RXQCGGRTAILOIN-UHFFFAOYSA-N ;
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Mephentermine (Wyamine, former brandname) is a cardiac stimulant.

It has been used as a treatment for low blood pressure.^[1]

Mephentermine belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding cardiac glycosides. Used in the treatment of heart failure.

^ Whittington RM (May 1963). "Mephentermine Sulphate as a Hypertensive Agent in General Practice". The Journal of the College of General Practitioners. 6 (2): 336–7. PMC 1878111. PMID 14000433.

[pmid14000433-1] Whittington RM (May 1963). "Mephentermine Sulphate as a Hypertensive Agent in General Practice". The Journal of the College of General Practitioners. 6 (2): 336–7. PMC 1878111. PMID 14000433.

[1]

Clinical data

Other names	methyl(2-methyl-1-phenylpropan-2-yl)amine
Routes of administration	IM/IV
ATC code	C01CA11 (WHO)
Legal status
Legal status	US: Schedule I (positional isomer of Etilamfetamine)
Pharmacokinetic data
Metabolism	Rapidly demethylated in the body followed by hydroxylation.
Excretion	Via urine (as unchanged and metabolites); more rapid in acidic urine.
Identifiers
IUPAC name N,2-dimethyl-1-phenylpropan-2-amine
CAS Number	100-92-5^Y
PubChem CID	3677
IUPHAR/BPS	7222
DrugBank	DB01365^Y
ChemSpider	3549^Y
UNII	TEZ91L71V4
KEGG	D08180^Y
ChEMBL	ChEMBL1201234^N
CompTox Dashboard (EPA)	DTXSID4023256
ECHA InfoCard	100.002.638
Chemical and physical data
Formula	C₁₁H₁₇N
Molar mass	163.264 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES N(C(Cc1ccccc1)(C)C)C
InChI InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3^Y Key:RXQCGGRTAILOIN-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Mephentermine

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