Pyridoxine

Pyridoxine
Pyridoxine
Clinical data
Other namesvitamin B6, pyridoxol[1] pyridoxine hydrochloride
AHFS/Drugs.comMonograph
License data
Pregnancy
category
Routes of
administration
By mouth, intravenous (IV), intramuscular (IM), subcutaneous
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-lifeseveral weeks (see #Metabolism for details)
Identifiers
  • 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.548 Edit this at Wikidata
Chemical and physical data
FormulaC8H11NO3
Molar mass169.180 g·mol−1
3D model (JSmol)
Melting point159 to 162 °C (318 to 324 °F)
  • OCc1cnc(C)c(O)c1CO
  • InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3 checkY
  • Key:LXNHXLLTXMVWPM-UHFFFAOYSA-N

Pyridoxine, is a form of vitamin B6 found commonly in food and used as a dietary supplement. As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.[4] It is used by mouth or by injection.[4]

It is usually well tolerated.[4] Occasionally side effects include headache, numbness, and sleepiness.[4] Normal doses are safe during pregnancy and breastfeeding.[4] Pyridoxine is in the vitamin B family of vitamins.[4] It is required by the body to metabolise amino acids, carbohydrates, and lipids.[4] Sources in the diet include fruit, vegetables, and grain.[5]

  1. ^ Dryhurst G (2012). "Electrochemistry of Biologically Important Pyridines". Electrochemistry of Biological Molecules. Elsevier. p. 562. ISBN 978-0-323-14452-0. Archived from the original on 30 December 2016.
  2. ^ "Pyridoxine Use During Pregnancy". Drugs.com. 27 April 2020. Archived from the original on 4 December 2020. Retrieved 6 May 2020.
  3. ^ "Pyridoxine 50mg Tablets - Summary of Product Characteristics (SmPC)". (emc). 27 April 2015. Archived from the original on 12 October 2013. Retrieved 6 May 2020.
  4. ^ a b c d e f g "Pyridoxine Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 30 December 2016. Retrieved 8 December 2016.
  5. ^ "Office of Dietary Supplements - Dietary Supplement Fact Sheet: Vitamin B6". ods.od.nih.gov. 11 February 2016. Archived from the original on 12 December 2016. Retrieved 30 December 2016.

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