Harvey J. Alter

Harvey J. Alter
Alter in 2020
Born
Harvey James Alter

(1935-09-12) September 12, 1935 (age 88)
EducationUniversity of Rochester (BA, MD)
National Institute of Health
University of Washington
Georgetown University
Known forHepatitis C
AwardsKarl Landsteiner Memorial Award (1992)
Lasker Award (2000)
Gairdner Foundation International Award (2013)
Nobel Prize for Medicine (2020)
Scientific career
FieldsVirology

Harvey James Alter (born September 12, 1935) is an American medical researcher, virologist, physician and Nobel Prize laureate, who is best known for his work that led to the discovery of the hepatitis C virus.[1] Alter is the former chief of the infectious disease section and the associate director for research of the Department of Transfusion Medicine at the Warren Grant Magnuson Clinical Center in the National Institutes of Health (NIH) in Bethesda, Maryland. In the mid-1970s, Alter and his research team demonstrated that most post-transfusion hepatitis cases were not due to hepatitis A or hepatitis B viruses. Working independently, Alter and Edward Tabor, a scientist at the U.S. Food and Drug Administration, proved through transmission studies in chimpanzees that a new form of hepatitis, initially called "non-A, non-B hepatitis" caused the infections, and that the causative agent was probably a virus. This work eventually led to the discovery of the hepatitis C virus in 1988,[1] for which he shared the Nobel Prize in Physiology or Medicine in 2020 along with Michael Houghton and Charles M. Rice.[2][3]

Alter has received recognition for the research leading to the discovery of the virus that causes hepatitis C. He was awarded the Distinguished Service Medal, the highest award conferred to civilians in United States government public health service, and the 2000 Albert Lasker Award for Clinical Medical Research.[4][5]

  1. ^ a b McHenry Harris; Randall E. Harris (2013). Epidemiology of Chronic Disease. Jones & Bartlett Publishers. ISBN 978-0-7637-8047-0.
  2. ^ "Press release: The Nobel Prize in Physiology or Medicine 2020". Nobel Foundation. Retrieved October 5, 2020.
  3. ^ Wu, Katherine J.; Victor, Daniel (October 5, 2020). "Nobel Prize in Medicine Awarded to Scientists Who Discovered Hepatitis C Virus - Harvey J. Alter, Michael Houghton and Charles M. Rice were jointly honored for their decisive contribution to the fight against blood-borne hepatitis, a major global health problem". The New York Times. Retrieved October 6, 2020.
  4. ^ "The Lasker Foundation". Archived from the original on February 25, 2008.
  5. ^ "Harvey J. Alter Curriculum Vitae". Archived from the original on September 4, 2005. Retrieved April 21, 2006.

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