Network motif

Network motifs are recurrent and statistically significant subgraphs or patterns of a larger graph. All networks, including biological networks, social networks, technological networks (e.g., computer networks and electrical circuits) and more, can be represented as graphs, which include a wide variety of subgraphs.

Network motifs are sub-graphs that repeat themselves in a specific network or even among various networks. Each of these sub-graphs, defined by a particular pattern of interactions between vertices, may reflect a framework in which particular functions are achieved efficiently. Indeed, motifs are of notable importance largely because they may reflect functional properties. They have recently[when?] gathered much attention as a useful concept to uncover structural design principles of complex networks.[1] Although network motifs may provide a deep insight into the network's functional abilities, their detection is computationally challenging.

  1. ^ Masoudi-Nejad A, Schreiber F, Razaghi MK Z (2012). "Building Blocks of Biological Networks: A Review on Major Network Motif Discovery Algorithms". IET Systems Biology. 6 (5): 164–74. doi:10.1049/iet-syb.2011.0011. PMID 23101871.

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