The Airbus A220 (formerly Bombardier CSeries) is a narrow-body airliner.
A220 may also refer to:
- Aerotrek A220, light sport aircraft, two-seater taildragger
- Alpine A220, sportscar racing prototype
- A220, model of Mercedes-Benz A-Class cars
- A220 road, between Erith and Bexleyheath in the UK
- RFA Wave Victor (A220), a Wave-class fleet support tanker