Michael J. Sailor | |
|---|---|
| Nationality | American |
| Alma mater | Harvey Mudd College (B.S., 1983) Northwestern University (M.S., Ph.D. 1988) |
| Known for | Porous silicon nanotechnology |
| Scientific career | |
| Fields | Nanotechnology, Porous silicon, Biomaterials |
| Institutions | University of California, San Diego (1990–) |
Michael J. Sailor is a nanotechnology researcher and professor at the University of California, San Diego.[1] Sailor is best known for his research on porous silicon, a nanostructured material that is prepared by electrochemical corrosion of crystalline silicon wafers.[2]
He pioneered the development of label-free biosensors from thin optical films of porous silicon.[3] He prepared the first microparticles and nanoparticles of porous silicon,[4] and harnessed the intrinsic photoluminescence of these formulations for in vitro and in vivo imaging applications.[5] He was the first to demonstrate time-gated luminescence imaging with these nanoparticles,[6] important because time-gating suppresses tissue autofluorescence that often compromises the fidelity of fluorescence images of biological tissues. He also adapted the concept of "Smart Dust" to the field of nanotechnology: the idea that microscopic particles can be manufactured with optical, chemical, and mechanical properties that can perform sensing, signaling, and motive functions.[7][8][9][10]
- ^ "Michael J. Sailor Biographical". UCSD Sailor Research Group. University of California, San Diego.
- ^ Sailor, Michael J. (2012). Porous silicon in practice preparation, characterization and applications. Weinheim: Wiley-VCH. p. 249. ISBN 9783527313785.
- ^ Lin, V.S.Y.; Motesharei, K.; Sailor, M. J.; Ghadiri, M. R. (31 October 1997). "A Porous Silicon-Based Optical Interferometric Biosensor". Science. 278 (5339): 840–843. Bibcode:1997Sci...278..840L. doi:10.1126/science.278.5339.840. PMID 9346478.
- ^ Heinrich, J.L.; Curtis, C.L.; Credo, G.M.; Kavanagh, K.L.; Sailor, M.J. (3 January 1992). "Luminescent colloidal Si suspensions from porous Si". Science. 255 (5040): 66–68. doi:10.1126/science.255.5040.66. PMID 17739915. S2CID 19694068.
- ^ Park, J.H.; Gu, L.; Rouslahti, E.; Bhatia, S.N.; Sailor, M.J. (22 February 2009). "Biodegradable luminescent porous silicon nanoparticles for in vivo applications". Nature Materials. 8 (4): 331–336. Bibcode:2009NatMa...8..331P. doi:10.1038/nmat2398. PMC 3058936. PMID 19234444.
- ^ Gu, L.; Hall, D.J.; Qin, Z.; Anglin, E.; Joo, J.; Mooney, D.J.; Howell, S.B.; Sailor, M.J. (12 August 2013). "In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles". Nature Communications. 4: 2326. Bibcode:2013NatCo...4.2326G. doi:10.1038/ncomms3326. PMC 4154512. PMID 23933660.
- ^ Sailor, M.J.; Link, J.R. (10 Feb 2005). "Smart Dust: nanostructured devices in a grain of sand". Chemical Communications (11): 1375–1383. doi:10.1039/b417554a. PMID 15756310.
- ^ Dovree, J.R.; Derfus, A.M.; Bhatia, S.N.; Sailor, M.J. (7 November 2004). "Manipulation of liquid droplets using amphiphilic, magnetic 1-D photonic crystal chaperones". Nature Materials. 3 (12): 896–899. doi:10.1038/nmat1253. PMID 15531887. S2CID 8177935.
- ^ Link, J.R.; Sailor, M.J. (June 19, 2003). "Smart Dust: Self-assembling, self-orienting photonic crystals of porous Si". Proceedings of the National Academy of Sciences. 100 (19): 10607–10610. Bibcode:2003PNAS..10010607L. doi:10.1073/pnas.1233824100. PMC 196851. PMID 12947036.
- ^ Schmedake, T.A.; Cunin, F.; Link, J.R.; Sailor, M.J. (16 September 2002). "Standoff detection of chemicals using porous silicon 'Smart Dust' particles". Advanced Materials. 14 (18): 1270–1272. doi:10.1002/1521-4095(20020916)14:18<1270::AID-ADMA1270>3.0.CO;2-R.