SARS-CoV-2 Lambda variant

The Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19.[1] It was first detected in Peru in August 2020.[2] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant[1] and designated it as a variant of interest.[3] On 16 March 2022, the WHO has de-escalated the Lambda variant to "previously circulating variants of concern".[4][5]

It has spread to at least 30 countries[6] around the world and is known to be more resistant to neutralizing antibodies compared to other strains.[7][8][9] There is evidence that suggests the Lambda variant is both more infectious and resistant to vaccines than the Alpha and/or Gamma variant.[10][11]

  1. ^ a b "Tracking SARS-CoV-2 variants". World Health Organization. Retrieved 2021-06-17.
  2. ^ "Weekly epidemiological update on COVID-19 - 15 June 2021" (PDF) (44 ed.). World Health Organization. 15 June 2021. Retrieved 2021-08-16. Lambda has been associated with substantive rates of community transmission in multiple countries, with rising prevalence over time concurrent with increased COVID-19 incidence. The earliest sequenced samples were reported from Peru in August 2020.
  3. ^ "Tracking SARS-CoV-2 variants". who.int. World Health Organization. Updated frequently.
  4. ^ "Tracking SARS-CoV-2 variants (updated 2022-03-16)". www.who.int. 2022-03-16. Archived from the original on 2022-03-17. Retrieved 2022-03-17.
  5. ^ "Tracking SARS-CoV-2 variants (updated 2022-03-07)". www.who.int. 2022-03-07. Archived from the original on 2022-03-15. Retrieved 2022-05-21.
  6. ^ "Covid 19 coronavirus: Ultra-contagious Lambda variant detected in Australia". New Zealand Herald. 6 July 2021.
  7. ^ Kimura, Izumi; Kosugi, Yusuke; Wu, Jiaqi; Yamasoba, Daichi; Butlertanaka, Erika P.; Tanaka, Yuri L.; Liu, Yafei; Shirakawa, Kotaro; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Tokunaga, Kenzo; Takaori-Kondo, Akifumi; Arase, Hisashi; Saito, Akatsuki; Nakagawa, So; Sato, Kei (28 July 2021). "SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance". bioRxiv 10.1101/2021.07.28.454085.
  8. ^ "COVID-19: Lambda variant may be more resistant to vaccines than other strains". World Is One News. 6 July 2021.
  9. ^ "Lambda variant: What is the new strain of Covid detected in the UK?". The Independent. 6 July 2021.
  10. ^ Mohammadi, Mehrdad; Shayestehpour, Mohammad; Mirzaei, Hamed (2021-07-01). "The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines". The Brazilian Journal of Infectious Diseases. 25 (4): 101606. doi:10.1016/j.bjid.2021.101606. ISSN 1413-8670. PMC 8367756. PMID 34428473.
  11. ^ Acevedo, Mónica L.; Alonso-Palomares, Luis; Bustamante, Andrés; Gaggero, Aldo; Paredes, Fabio; Cortés, Claudia P.; Valiente-Echeverría, Fernando; Soto-Rifo, Ricardo (2021-07-01). "Infectivity and immune escape of the new SARS-CoV-2 variant of interest Lambda". medRxiv 10.1101/2021.06.28.21259673v1.

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