Trans fat is a type of unsaturated fat that occurs in foods.[1][2] Small amounts of trans fats occur naturally, but large amounts are found in some processed foods made with partially hydrogenated oils.[1][2] Because consumption of trans fats is associated with increased risk for cardiovascular diseases, artificial trans fats are highly regulated or banned in many countries.[3][4][5][6][7] However, they are still widely consumed in developing nations where they are associated with increased risk of diabetes, cardiovascular diseases, and death.[8]
In 2015, the US Food and Drug Administration (FDA) stated that artificial trans fats from partially hydrogenated oils were not generally recognized as safe (GRAS), and the use of such oils and trans fats should be limited or eliminated from manufactured foods.[2] Numerous governing bodies, including the European Union, Canada, and Australia/New Zealand, followed with restrictions or bans on the use of partially hydrogenated oils and trans fats in food manufacturing.[1][9] The World Health Organization (WHO) had set a goal to make the world free from industrially produced trans fat by the end of 2023.[10] The goal was not met, and the WHO announced another goal in 2024 "for accelerated action until 2025 to complete this effort".[7]
Trans fatty acids (also called trans-unsaturated fatty acids) are derived from trans fats, which are triglycerides (esters of glycerin). Trans fats are converted to trans fatty acids in the digestive tract prior to absorption.
^ abc"Trans fat". US Food and Drug Administration. 30 April 2024. Archived from the original on 18 June 2019. Retrieved 24 January 2025.
^Gormley JJ, Juturu V (2010). "Partially Hydrogenated Fats in the US Diet and Their Role in Disease". In De Meester F, Zibadi S, Watson RR (eds.). Modern Dietary Fat Intakes in Disease Promotion. Nutrition and Health. Totowa, NJ: Humana Press. pp. 85–94. doi:10.1007/978-1-60327-571-2_5. ISBN978-1-60327-571-2.