ZW sex-determination system

ZW sex determination in birds (as exemplified with chickens)

The ZW sex-determination system is a chromosomal system that determines the sex of offspring in birds, some fish and crustaceans such as the giant river prawn, some insects (including butterflies and moths), the schistosome family of flatworms, and some reptiles, e.g. majority of snakes, lacertid lizards and monitors, including Komodo dragons. It is also present in some plants, where it has evolved independently on many occasions, characterizing at least 22% of plants with documented sex chromosomes.[1][2] The letters Z and W are used to distinguish this system from the XY sex-determination system. In the ZW system, females have a pair of dissimilar ZW chromosomes, and males have two similar ZZ chromosomes.

In contrast to the XY sex-determination system and the X0 sex-determination system, where the sperm determines the sex, in the ZW system, the ovum determines the sex of the offspring. Males are the homogametic sex (ZZ), while females are the heterogametic sex (ZW). The Z chromosome is larger and has more genes, similarly to the X chromosome in the XY system.

  1. ^ Renner, S.S. (January 2025). "Female heterogamety (ZW systems) in 22% of flowering plants with sex chromosomes – theoretical expectations and correlates". American Journal of Botany: e70006. doi:10.1002/ajb2.70006. PMID 39980177.
  2. ^ Zhou, Ran; Macaya-Sanz, David; Carlson, Craig H.; thirteen others, and (14 February 2020). "A willow sex chromosome reveals convergent evolution of complex palindromic repeats". Genome Biology. 21 (1): 38. doi:10.1186/s13059-020-1952-4. PMC 7023750. PMID 32059685.

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