Mannose

Mannose

D-Mannopyranose

Fischer projections
Names
IUPAC name
Mannose
Systematic IUPAC name
(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Identifiers
ChEMBL
ChemSpider
KEGG
MeSH Mannose
UNII
Properties
C6H12O6
Molar mass 180.156 g·mol−1
Appearance white solid
Density 1.554 g/cm3
Melting point 132 °C (270 °F; 405 K)
-102.90·10−6 cm3/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Mannose is a sugar with the formula HOCH2(CHOH)4CHO. It is one of the monomers of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several congenital disorders of glycosylation are associated with mutations in enzymes involved in mannose metabolism.[1]

Mannose is not an essential nutrient; it can be produced in the human body from glucose, or converted into glucose. Mannose provides 2–5 kcal/g. It is partially excreted in the urine.

  1. ^ Freeze, H. H.; Sharma, V. (2010). "Metabolic manipulation of glycosylation disorders in humans and animal models". Seminars in Cell & Developmental Biology. 21 (6): 655–662. doi:10.1016/j.semcdb.2010.03.011. PMC 2917643. PMID 20363348.

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