U.S. Route 43

U.S. Route 43
US 43 highlighted in red
Route information
Length	410 mi[1] (660 km)
Existed	1934[2][3]–present
Major junctions
South end	US 90 in Prichard, AL
Major intersections	I-65 in Satsuma, AL US 84 in Grove Hill, AL US 80 in Demopolis, AL US 11 from Eutaw to Tuscaloosa, AL I-20 / I-59 south of Knoxville, AL I-22 / US 78 in Hamilton, AL US 72 from Muscle Shoals to near Killen, AL US 64 in Lawrenceburg, TN
North end	US 31 / US 412 in Columbia, TN
Location
Country	United States
States	Alabama, Tennessee
Counties	AL: Mobile, Washington, Clarke, Marengo, Greene, Tuscaloosa, Fayette, Marion, Franklin, Colbert, Lauderdale TN: Lawrence, Maury
Highway system
United States Numbered Highway System List Special Divided
Alabama State Highway System Interstate US State
Tennessee State Routes Interstate US State
← US 42 US → US 44 ← SR 42 AL → SR 44 ← SR 41 TN → SR 43

U.S. Route 43 (US 43) is a 410-mile-long (660 km) north–south United States Highway in the Southern states of Alabama and Tennessee. It travels from Prichard, Alabama, to Columbia, Tennessee. The highway's southern terminus is in Prichard, at an intersection with US 90, and its northern terminus is in Columbia at an intersection with US 31/US 412/US 412 Bus.

In Alabama and Tennessee, all of the U.S. Highways in each state have one or more unsigned state highways designated along its length. US 43 travels concurrently with Alabama State Route 13 (SR 13) from its southern terminus to an intersection in southeastern Fayette County. For the rest of its length in the state, US 43 is concurrent with signed state highways. In Tennessee, US 43 travels concurrently with Tennessee State Route 6 (SR 6) along its entire length in the state. It also has an unsigned concurrency with SR 227 between Saint Joseph and Loretto.