Enantiomer

(S)-(+)-lactic acid (left) and (R)-(–)-lactic acid (right) are nonsuperposable mirror images of each other.

In chemistry, an enantiomer (/ɪˈnænti.əmər, ɛ-, -oʊ-/[1] ih-NAN-tee-ə-mər; from Ancient Greek ἐναντίος (enantíos) 'opposite', and μέρος (méros) 'part') – also called optical isomer,[2] antipode,[3] or optical antipode[4] – is one of two stereoisomers that are nonsuperposable onto their own mirror image. Enantiomers of each other are much like one's right and left hands; without mirroring one of them, hands cannot be superposed onto each other.[5] It is solely a relationship of chirality and the permanent three-dimensional relationships among molecules or other chemical structures: no amount of re-orientiation of a molecule as a whole or conformational change converts one chemical into its enantiomer. Chemical structures with chirality rotate plane-polarized light.[6] A mixture of equal amounts of each enantiomer, a racemic mixture or a racemate, does not rotate light.[7][8] [9]

Stereoisomers include both enantiomers and diastereomers. Diastereomers, like enantiomers, share the same molecular formula and are also nonsuperposable onto each other; however, they are not mirror images of each other.[10]

  1. ^ "Enantiomer: Definition & Meaning". Dictionary.com. Retrieved 2024-04-26.
  2. ^ Chemistry (IUPAC), The International Union of Pure and Applied. "IUPAC - optical isomers (O04308)". goldbook.iupac.org. doi:10.1351/goldbook.O04308. Retrieved 2022-11-17.
  3. ^ Chemistry (IUPAC), The International Union of Pure and Applied. "IUPAC - antipodes (A00403)". goldbook.iupac.org. doi:10.1351/goldbook.A00403. Retrieved 2022-11-17.
  4. ^ Chemistry (IUPAC), The International Union of Pure and Applied. "IUPAC - optical antipodes (O04304)". goldbook.iupac.org. doi:10.1351/goldbook.O04304. Retrieved 2022-11-17.
  5. ^ McConathy, Jonathan; Owens, Michael J. (2003). "Stereochemistry in Drug Action". Primary Care Companion to the Journal of Clinical Psychiatry. 5 (2): 70–73. doi:10.4088/pcc.v05n0202. ISSN 1523-5998. PMC 353039. PMID 15156233.
  6. ^ "Chirality and Optical Activity". chemed.chem.purdue.edu. Retrieved 2022-11-17.
  7. ^ Chemistry (IUPAC), The International Union of Pure and Applied. "IUPAC - racemic (R05026)". goldbook.iupac.org. doi:10.1351/goldbook.R05026. Retrieved 2022-11-17.
  8. ^ Chemistry (IUPAC), The International Union of Pure and Applied. "IUPAC - racemate (R05025)". goldbook.iupac.org. doi:10.1351/goldbook.R05025. Retrieved 2022-11-17.
  9. ^ Weber, Erin. "Library Guides: CHEM 221: Stereochemistry / Isomerism". libraryguides.salisbury.edu. Retrieved 2022-11-17.
  10. ^ Smith, Michael B.; March, Jerry (2007), Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th ed.), New York: Wiley-Interscience, ISBN 978-0-471-72091-1

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